Hyperelastic models for the human zona pellucida and their implications on shear modulus estimation in the clinical practice.

ABSTRACT: It has long been speculated that the mechanical properties of the human oocyte can be an indicator for oocyte viability. Recent studies have demonstrated that embryo implantation rates, following Intra-Cytoplasmic Sperm Injection (ICSI) procedures, may be increased if the shear modulus value of the oocyte Zona Pellucida (ZP) is taken into consideration during embryo transfer. The shear modulus was determined by an iterative oocyte specific finite element (FE) analysis based on the clinical ICSI data. Nevertheless, the results obtained from the computational analysis may depend on the choice of the constitutive model used for the ZP. In the current study, three different hyper-elastic strain energy density functions (SEDF's) are considered. The Neo-Hookean (NH), Mooney-Rivlin (MR) and Ogden

SUBMITTER: Priel E 

PROVIDER: S-EPMC11682203 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature