Impact of hospital-related indicators on healthcare-associated infections and appropriateness of antimicrobial use according to a national dataset.

ABSTRACT: Healthcare-associated infections (HAIs) represent a major threat in Europe. Infection prevention and control (IPC) measures are crucial to lower their occurrence, as well as antimicrobial stewardship to ensure appropriate use of antibiotics. Starting from Italian national data, this study aimed at: (i) describing IPC indicators, prevalence of HAIs, antimicrobial use and appropriateness of antibiotic use in Italy; (ii) estimating effects of IPC variables on HAI prevalence and on the proportion of antibiotics without specific reason. Based on data collected for Italy during the ECDC PPS-2 Point Prevalence Survey, descriptive statistics were computed at national and macro-regional level. Causal assumption-informed regression models were then built to estimate the impact of structural determin

SUBMITTER: Garlasco J 

PROVIDER: S-EPMC11682244 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature