Gas transport mechanisms during high-frequency ventilation.

ABSTRACT: By virtue of applying small tidal volumes, high-frequency ventilation is advocated as a method of minimizing ventilator-induced lung injury. Lung protective benefits are established in infants, but not in other patient cohorts. Efforts to improve and extend the lung protection potential should consider how fundamental modes of gas transport can be exploited to minimize harmful tidal volumes while maintaining or improving ventilation.This research investigates different models of gas transport during high-frequency ventilation and discusses the extent to which the gas transport mechanisms are considered in each. The research focuses on the rationale for current ventilation protocols, how they were informed by these models, and investigates alternative protocols that may improve gas transpor

SUBMITTER: Scott TJA 

PROVIDER: S-EPMC11682653 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature