Molecular characterization of antibiotic resistance in bacteria from daycare centres in Ile-Ife, Nigeria.

ABSTRACT:

Background

Antibiotic resistance is an escalating global health issue, with particularly severe implications in low- and middle-income countries (LMICs) such as Nigeria. This study examines antibiotic-resistant bacteria's prevalence and molecular characteristics in daycare centres in Ile-Ife, Nigeria, where high antibiotic use and limited infection control measures present significant challenges.

Methods

Between November 2017 and July 2019, samples were collected from 20 daycare centres, including swabs from fomites and children. Bacterial isolates were identified and assessed for antibiotic susceptibility using standard methods. Molecular techniques, including PCR, were employed to detect resistance genes such as blaSHV, tetA, dfr1 and mecA.

R

SUBMITTER: Wilkie ED 

PROVIDER: S-EPMC11683008 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature