Maternal asthma during pregnancy and the likelihood of neurodevelopmental disorders in offspring.

ABSTRACT:

Introduction

Asthma is the most common chronic disease during pregnancy. Maternal asthma has been associated with a multitude of unwanted pregnancy outcomes, in some studies also with neurodevelopmental disorders. Here we investigated associations between maternal asthma and neurodevelopmental disorders.

Material and methods

We studied a retrospective population-based cohort of 1 271 439 mother-child pairs from singleton live births in Finland between the years 1996-2018. We used multiple high-cover registers for data collection. Adjusted unconditional Cox regression models were used to investigate associations between maternal asthma, asthma medication used during pregnancy, and offspring's neurodevelopmental disorder diagnoses.

Results

We identified 106 163 mother-c

SUBMITTER: Kemppainen M 

PROVIDER: S-EPMC11683540 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature