Association between number of medications and indicators of potentially inappropriate polypharmacy: a population-based cohort of older adults in Quebec, Canada.

ABSTRACT:

Background

As the number of medications increases, the appropriateness of polypharmacy may become questionable due to the heightened risk of medication-related harm.

Objectives

(1) To investigate the relationship between the number of current medications used by older adults and three indicators of potentially inappropriate polypharmacy: (a) the mean number of potentially inappropriate medications (PIMs), (b) the average count of drug-drug interactions, and (c) the anticholinergic burden; (2) To characterize the population-based burden of potentially inappropriate polypharmacy by calculating the proportion of individuals with these indicators.

Design

We conducted a population-based observational study using the Quebec Integrated Chronic Disease Surveillance System.

SUBMITTER: Campeau Calfat A 

PROVIDER: S-EPMC11683794 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature