Identifying brain targets for real-time fMRI neurofeedback in chronic pain: insights from functional neurosurgery.

ABSTRACT:

Background

The lack of clearly defined neuromodulation targets has contributed to the inconsistent results of real-time fMRI-based neurofeedback (rt-fMRI-NF) for the treatment of chronic pain. Functional neurosurgery (funcSurg) approaches have shown more consistent effects in reducing pain in patients with severe chronic pain.

Objective

This study aims to redefine rt-fMRI-NF targets for chronic pain management informed by funcSurg studies.

Methods

Based on independent systematic reviews, we identified the neuromodulation targets of the rt-fMRI-NF (in acute and chronic pain) and funcSurg (in chronic pain) studies. We then characterized the underlying functional networks using a subsample of the 7 T resting-state fMRI dataset from the Human Connectome Project. Principal

SUBMITTER: Liu D 

PROVIDER: S-EPMC11683833 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature