Novel immunoinflammatory blood markers in Graves' orbitopathy: insights into activity and severity.

ABSTRACT:

Objective

This prospective case-control study examined the novel immunoinflammatory markers obtained from blood counts of patients with Graves' orbitopathy (GO), Graves' disease (GD) and healthy subjects.

Methods

Demographic data, white cell count parameters, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), platelet-to-neutrophil ratio (PNR), red cell distribution width (RDW), RDW-to-platelet ratio (RDW/PLT), MPV-to-lymphocyte ratio (MPV/ALC), eosinophil-to-lymphocyte ratio (ELR) and systemic immune-inflammatory index (SII) were evaluated. The European Group on Graves Orbitopathy scale and Clinical Activity Score were used for clinical activity and severity assessment.

Results

The GO group showed significantly highe

SUBMITTER: Abounoori M 

PROVIDER: S-EPMC11683961 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature