The FunCoup Cytoscape App: multi-species network analysis and visualization.

ABSTRACT:

Motivation

Functional association networks, such as FunCoup, are crucial for analyzing complex gene interactions. To facilitate the analysis and visualization of such genome-wide networks, there is a need for seamless integration with powerful network analysis tools like Cytoscape.

Results

The FunCoup Cytoscape App integrates the FunCoup web service API with Cytoscape, allowing users to visualize and analyze gene interaction networks for 640 species. Users can input gene identifiers and customize search parameters, using various network expansion algorithms like group or independent gene search, MaxLink, and TOPAS. The app maintains consistent visualizations with the FunCoup website, providing detailed node and link information, including tissue and pathway gene annotations.

SUBMITTER: Buzzao D 

PROVIDER: S-EPMC11684335 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature