Time to Glaucoma Progression Detection by Optical Coherence Tomography in Individuals of African and European Descents.

ABSTRACT:

Purpose

To examine the time to detectable retinal nerve fiber layer thickness (RNFLT) progression by optical coherence tomography (OCT) among glaucoma patients of African descent (AD) and European descent (ED).

Design

Retrospective cohort study.

Methods

AD and ED glaucoma eyes from the Diagnostic Innovations in Glaucoma Study (DIGS)/African Descent and Glaucoma Evaluation Study (ADAGES) with ≥2 years/4 visits of optic nerve head RNFLT measurements were included after homogenization on age, diagnosis, and baseline visual field (VF) measurement. RNFLT variability estimates based on linear mixed-effects models were used to simulate longitudinal RNFLT data for both races. Times to trend-based RNFLT progression detection were calculated under standardized scenarios (same R

SUBMITTER: Wu JH 

PROVIDER: S-EPMC11684426 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature