The phytohormone abscisic acid enhances remyelination in mouse models of multiple sclerosis.

ABSTRACT:

Introduction

Over the past few decades, there has been a sudden rise in the incidence of Multiple Sclerosis (MS) in Western countries. However, current treatments often show limited efficacy in certain patients and are associated with adverse effects, which highlights the need for safer and more effective therapeutic approaches. Environmental factors, particularly dietary habits, have been observed to play a substantial role in the development of MS. In this study, we are the first to investigate the potential protective effect of the phytohormone abscisic acid (ABA) in MS. ABA, which is abundant in fruits such as figs, apricots and bilberries, is known to cross the blood-brain barrier and has demonstrated neuroprotective effects in conditions like depression and Alzheimer's diseas

SUBMITTER: Van Gaever F 

PROVIDER: S-EPMC11685095 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature