The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry.

ABSTRACT: Fruit ripening is a highly-orchestrated process that requires the fine-tuning and precise control of gene expression, which is mainly governed by phytohormones, epigenetic modifiers, and transcription factors. How these intrinsic regulators coordinately modulate the ripening remains elusive. Here we report the identification and characterization of FvALKBH10B as an N⁶-methyladenosine (m⁶A) RNA demethylase necessary for the normal ripening of strawberry (Fragaria vesca) fruit. FvALKBH10B is induced by phytohormone abscisic acid (ABA), and ABA-Responsive Element Binding Factor 3 (FvABF3), a master regulator in ABA signaling, is responsible for this activation. FvALKBH10B mutation leads to a delay in fruit ripening and causes global m⁶A hypermethylation of 185

SUBMITTER: Tang R 

PROVIDER: S-EPMC11685502 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature