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Infrared thermal modulation endoscopy for label-free tumor detection.


ABSTRACT: In optical imaging of solid tumors, signal contrasts derived from inherent tissue temperature differences have been employed to distinguish tumor masses from surrounding tissue. Moreover, with the advancement of active infrared imaging, dynamic thermal characteristics in response to exogenous thermal modulation (heating and cooling) have been proposed as novel measures of tumor assessment. Contrast factors such as the average rate of temperature changes and thermal recovery time constants have been investigated through an active thermal modulation imaging approach, yielding promising tumor characterization results in a xenograft mouse model. Here, to assess its clinical potential, we developed and deployed an endoscopic infrared thermal modulation imaging system, incorporating anti-reflect

SUBMITTER: Kim S 

PROVIDER: S-EPMC11685564 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature