Untangling areas of improvement in secondary prevention of ischemic stroke in patients with atrial fibrillation.

ABSTRACT: Improvement of post-stroke outcomes relies on patient adherence and appropriate therapy maintenance by physicians. However, comprehensive evaluation of these factors is often overlooked. This study assesses secondary stroke prevention by differentiating patient adherence to antithrombotic treatments (ATT) from physician-initiated interruptions or switches. We analyzed a population-based retrospective cohort (n = 10,343) of post-stroke patients with atrial fibrillation using the VID database (2010-2017). Secondary prevention was evaluated based on patients' primary and secondary adherence to ATT at two years (percentage of days covered-PDC-and persistence/discontinuation) and physician prescription patterns (initiation, interruption, switching, restart). E-prescription and dispensing data w

SUBMITTER: Sanchez-Saez F 

PROVIDER: S-EPMC11685578 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature