Multimodal cadmium resistance and its regulatory networking in Pseudomonas aeruginosa strain CD3.

ABSTRACT: Cadmium, a toxic heavy metal, poses significant global concern. A strain of the genus Pseudomonas, CD3, demonstrating significant cadmium resistance (up to 3 mM CdCl₂.H₂O) was identified from a pool of 26 cadmium-resistant bacteria isolated from cadmium-contaminated soil samples from Malda, India. The minimum inhibitory concentrations (MICs) for cadmium and other heavy metals/metalloids were determined with clarity using a modified chemically-defined medium inoculated with variable inoculum density. Formation of biofilm enabled CD3 cells to resist up to 0.75 mM CdCl₂.H₂O. Survival and growth of CD3 cells in presence of > 1 mM CdCl₂.H₂O was dependent on efflux mechanism. Efflux mechanism in CD3 was confirmed by atomic absorpt

SUBMITTER: Chatterjee S 

PROVIDER: S-EPMC11685661 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature