Neuromorphic-enabled video-activated cell sorting.

ABSTRACT: Imaging flow cytometry allows image-activated cell sorting (IACS) with enhanced feature dimensions in cellular morphology, structure, and composition. However, existing IACS frameworks suffer from the challenges of 3D information loss and processing latency dilemma in real-time sorting operation. Herein, we establish a neuromorphic-enabled video-activated cell sorter (NEVACS) framework, designed to achieve high-dimensional spatiotemporal characterization content alongside high-throughput sorting of particles in wide field of view. NEVACS adopts event camera, CPU, spiking neural networks deployed on a neuromorphic chip, and achieves sorting throughput of 1000 cells/s with relatively economic hybrid hardware solution (~$10 K for control) and simple-to-make-and-use microfluidic infrastructure

SUBMITTER: He W 

PROVIDER: S-EPMC11685671 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature