Temporal evolution of insecticide resistance and bionomics in Anopheles funestus, a key malaria vector in Uganda.

ABSTRACT: Insecticide resistance escalation is decreasing the efficacy of vector control tools. Monitoring vector resistance is paramount in order to understand its evolution and devise effective counter-solutions. In this study, we monitored insecticide resistance patterns, vector population bionomics and genetic variants associated with resistance over 3 years from 2021 to 2023 in Uganda. Anopheles funestus s.s was the predominant species in Mayuge but with evidence of hybridization with other species of the An. funestus group. Sporozoite infection rates were relatively very high with a peak of 20.41% in March 2022. Intense pyrethroid resistance was seen against pyrethroids up to 10-times the diagnostic concentration but partial recovery of susceptibility in PBO synergistic assays. Among bednets,

SUBMITTER: Oruni A 

PROVIDER: S-EPMC11685729 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature