Patient and physician expectations regarding disease and treatment of advanced HCC: The prospective PERCEPTION1 study.

ABSTRACT:

Background & aims

We aimed to explore patient expectations regarding their treatments and prognosis in comparison to physicians' assessments in patients with advanced hepatocellular carcinoma (HCC) receiving systemic treatments.

Methods

We prospectively enrolled 205 patients in France and Belgium with Barcelona Clinic Liver Cancer (BCLC) stage B/C HCC receiving systemic treatment (NCT04823754). Patients completed a 28-question survey and the hospital anxiety and depression scale (HADS), while physicians filled a 17-question survey after the initial consultation. Univariate and multivariate models were used to assess factors associated with concordant patient-physician responses, HADS, as well as predicted (by physicians) and observed overall survival.

Results

Patients

SUBMITTER: Nault JC 

PROVIDER: S-EPMC11686048 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature