Magnetosensitivity of tightly bound radical pairs in cryptochrome is enabled by the quantum Zeno effect.

ABSTRACT: The radical pair mechanism accounts for the magnetic field sensitivity of a large class of chemical reactions and is hypothesised to underpin numerous magnetosensitive traits in biology, including the avian compass. Traditionally, magnetic field sensitivity in this mechanism is attributed to radical pairs with weakly interacting, well-separated electrons; closely bound pairs were considered unresponsive to weak fields due to arrested spin dynamics. In this study, we challenge this view by examining the FAD-superoxide radical pair within cryptochrome, a protein hypothesised to function as a biological magnetosensor. Contrary to expectations, we find that this tightly bound radical pair can respond to Earth-strength magnetic fields, provided that the recombination reaction is strongly asymme

SUBMITTER: Denton MCJ 

PROVIDER: S-EPMC11686217 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature