Modulating the human gut microbiome and health markers through kombucha consumption: a controlled clinical study.

ABSTRACT: Fermented foods are becoming more popular due to their purported links to metabolic health and the gut microbiome. However, direct clinical evidence for the health claims is lacking. Here, we describe an eight-week clinical trial that explored the effects of a four-week kombucha supplement in healthy individuals consuming a Western diet, randomized into the kombucha (n = 16) or control (n = 8) group. We collected longitudinal stool and blood samples to profile the human microbiome and inflammation markers. We did not observe significant changes in either biochemical parameters or levels of circulating markers of inflammation across the entire cohort. However, paired analysis between baseline and end of intervention time points within kombucha or control groups revealed increases in fasting

SUBMITTER: Ecklu-Mensah G 

PROVIDER: S-EPMC11686376 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature