The association between adverse childhood experiences and adult cardiac function in the UK Biobank.

ABSTRACT:

Aims

The importance of early life factors in determining health in later adulthood is increasingly recognized. This study evaluated the association of adverse childhood experiences (ACEs) with cardiovascular magnetic resonance (CMR) phenotypes.

Methods and results

UK Biobank participants who had completed CMR and the self-reported questionnaire on traumatic childhood experiences were included. Images were analysed using automated pipelines to extract measures of left and right ventricular (LV and RV) structure and function, myocardial character, and arterial compliance. Multivariable linear regression was used to estimate the association of childhood adversity with CMR phenotypes adjusting for age, sex, deprivation, education, obesity, smoking, alcohol intake, exercise level

SUBMITTER: Quiroz JC 

PROVIDER: S-EPMC11686440 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature