Global, regional and national burden due to retinoblastoma in children aged younger than 10 years from 1990 to 2021.

ABSTRACT:

Background

Retinoblastoma (RB), an aggressive intraocular malignancy, significantly adds to the global disease burden in early childhood. This study offers insights into the global burden of retinoblastoma (RB) in children aged 0-9 years, examining incidence, mortality, and DALYs from 1990 to 2021, across age, sex, location, and SDI levels. It aims to inform health policy, resource allocation, and RB combat strategies.

Methods

Data were retrieved from newly released Global Burden of Disease (GBD) study. The measures were estimated both as numerical counts and age-standardised rates per 100,000 population. Joinpoint regression analysis was used to rigorously examine temporal trends, estimating the average annual percentage change (AAPC). Spearman's correlation test was used t

SUBMITTER: Li C 

PROVIDER: S-EPMC11686879 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature