CircRNA profiling reveals the regulatory role of circPAN3 in Hezuo boars Sertoli cell growth.

ABSTRACT:

Background

The Hezuo (HZ) pig, a famous indigenous breed in China, is characterized by precocious puberty compared with foreign-introduced pig breeds. Sexual maturation is a complex physiological process, and in recent years, circular RNAs (circRNAs), a new class of noncoding RNAs with endogenous regulatory functions, have been shown to play important roles in regulating sexual maturation. However, the dynamic expression and regulatory mechanism of circRNAs during sexual maturation in HZ pigs remain unclear. In this study, we performed RNA sequencing and bioinformatics analysis to reveal circRNA expression patterns in the testes of HZ boars at 30 days (sexual immaturity; Ha) and 120 days (sexual maturity; Hb), with Landrace (LC) boars of the same age (La and Lb) as controls. Subseq

SUBMITTER: Shi H 

PROVIDER: S-EPMC11686915 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature