Improving hydraulic performance of the left atrial assist device using computational fluid dynamics.

ABSTRACT:

Background

The left atrial assist device (LAAD) is a novel continuous-flow pump designed to treat patients with heart failure with preserved ejection fraction, a growing type of heart failure, but with limited device-treatment options. The LAAD is implanted in the mitral plane and pumps blood from the left atrium into the left ventricle. The purpose of this study was to refine the initial design of the LAAD, using results from computational fluid dynamics (CFD) analyses to inform changes that could improve hydraulic performance and flow patterns within the LAAD.

Methods

The initial design and three variations were simulated, exploring changes to the primary impeller blades, the housing shape, and the number, size, and curvature of the diffuser vanes. Several pump rotational

SUBMITTER: Goodin MS 

PROVIDER: S-EPMC11687210 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature