The burden of medical contraindications to corneal donation: Time for review.

ABSTRACT: Corneal graft (keratoplasty) is the most common allograft in the world, but the imbalance between the number of donors and the number of patients waiting for transplants is abysmal on a global scale and varies enormously from one country to another. The risk of transmission of systemic diseases from donor to recipient is demonstrably low. In over 50 years and an estimated 2.5 million transplants, only 8 cases of rabies, 2 cases of hepatitis B and 2 cases of Creutzfeldt-Jakob disease (CJD) have been documented. Conversely, other cases of rabies, HIV, hep C, hep B and CJD have not been transmitted via keratoplasty. The list of medical contraindications (CI) to corneal donation also includes diseases for which no actual, only theoretical, risk has been identified, in particular, neurodegenera

SUBMITTER: Dorado-Cortez O 

PROVIDER: S-EPMC11687701 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature