Association between potential factors and dry eye disease: A systematic review and meta-analysis.

ABSTRACT:

Background

The 2017 TFOS DEWS II report provided an overview of the epidemiology of dry eye disease (DED) and identified several potential risk factors. This study aimed to conduct a meta-analysis on these potential risk factors.

Methods

A comprehensive systematic search was conducted in PubMed, Embase, Web of Science, and Cochrane Library databases to include observational studies. Two researchers independently extracted adjusted odds ratios (AORs) and their 95% confidence intervals (CIs), and a random-effects model was used to combine the data. Results were reported using odds ratios (ORs) and their 95% CIs.

Results

The meta-analysis results showed that the risk factors for DED were smoking (OR 1.18, 95% CI 1.07-1.29), alcohol consumption (OR 1.18, 95% CI 1.03-1.35)

SUBMITTER: Yang K 

PROVIDER: S-EPMC11688006 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature