Bioinformatics-based discovery of biomarkers and immunoinflammatory infiltrates in hip fractures complicating deep vein thrombosis: A STROBE.

ABSTRACT: Deep vein thrombosis due to hip fracture is a normally concomitant symptom when fracture arrival at middle-aged and olderly people, but its molecular mechanism is still not well explained. We hypothesized that there are several key biomarkers and associated signaling pathways that could predict deep vein thrombosis, our goal was to employ bioinformatics to find important biomarkers of deep vein thrombosis and the results of immune infiltration. From the GEO-NCBI database, venous thrombosis expression profiles were chosen, and hip fracture and venous thrombosis gene datasets were gathered from a comprehensive database that can be searched for human genes, which is called GeneCards. Building networks between proteins with the STRING web application, and Kyoto Encyclopedia of Genes and Genome

SUBMITTER: Fu Z 

PROVIDER: S-EPMC11688061 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature