Metabolomic profile and its association with the diagnosis of prostate cancer: a systematic review.

ABSTRACT:

Objective

To determine the association of a metabolomic profile with the diagnosis of localized prostate cancer.

Methods

We conducted a search strategy in MEDLINE (OVID), EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) from 2008 to the present. We included Clinical trials and analytical and descriptive observational studies that reported metabolite results and metabolite profiles in serum, tissue, urine, and seminal fluid. All studies used metabolomic techniques such as MS and MRI to identify patients with localized prostate cancer compared with patients without cancer. We used QUADAS 2 to assess the risk of bias.

Results

We found 1248 studies with the search strategy. Finally, 14 case-control studies were included. Serum was the prima

SUBMITTER: Salinas Pita AP 

PROVIDER: S-EPMC11688254 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature