Power-free plasma separation based on negative magnetophoresis for rapid biochemical analysis.

ABSTRACT: We present a versatile platform for label-free magnetic separation of plasma, tailored to accommodate diverse environments. This innovative device utilizes an advanced long-short alternating double Halbach magnetic array, specifically engineered for optimal magnetic separation. The array's adaptability allows for seamless integration with separation channels of varying sizes, enabling static separation of whole blood. The platform has a highly flexible processing throughput, spanning from 100 μL to 3 mL per separation cycle without sacrificing separation efficiency. A key aspect of this device is its power-free operation throughout the separation process, obviating the complexity of conventional separation devices. Its effectiveness is demonstrated by the extraction of 40 μL of plasma from

SUBMITTER: Zeng L 

PROVIDER: S-EPMC11688449 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature