A nomogram model to predict the high risk of lower live birth probability in young women undergoing the first IVF-ET cycle: a retrospective study.

ABSTRACT:

Objective

To build a prediction nomogram for early prediction of live birth probabilities according to number of oocytes retrieved in women ≤ 35 years of age.

Methods

A prediction model was built including 9265 infertile women ≤ 35 years of age accepting their first ovum pick-up cycle from January 2018 to December 2022. Least absolute shrinkage and selection operator (LASSO) regression was performed to identify independent predictors and establish a nomogram to predict reproductive outcomes. Both discrimination and calibration were assessed by bootstrapping with 1000 resamples.

Results

The critical threshold for the number of retrieved oocytes associated with cumulative live birth was determined as 10.5 (AUC: 0.824). Consequently, a nomogram was constructed to predict

SUBMITTER: Liu C 

PROVIDER: S-EPMC11693585 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature