Neonatal body composition, salivary feeding gene expression, and feeding outcomes in infants of diabetic mothers.

ABSTRACT:

Introduction

Infants of diabetic mothers (IDMs) may exhibit decreased oral intake, requiring nasogastric feedings and prolonged hospitalization. The objective of this study was to explore whether saliva serves as an informative biofluid for detecting expression of hunger signaling and energy homeostasis modulator genes and to perform exploratory analyses examining expression profiles, body composition, and feeding outcomes in late preterm and term IDMs and infants born to mothers with normoglycemia during pregnancy.

Methods

In this prospective cohort pilot study, infants born at ≥ 35 weeks' gestation to mothers with gestational or type II diabetes (IDM cohort) and normoglycemic mothers (control cohort) were recruited. The presence of known hunger signaling genes: 5'AMP-activ

SUBMITTER: Azuma D 

PROVIDER: S-EPMC11693610 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature