Influenza vaccine effectiveness in immunocompromised patients with cancer: A Danish nationwide register-based cohort study.

ABSTRACT:

Background

Influenza vaccination is free of charge for Danish citizens with acquired immunodeficiency but recommendations do not specifically target patients with cancer. This study investigated whether influenza vaccination reduces the main outcome of overall mortality and the secondary outcomes of influenza requiring treatment, pneumonia, myocardial infarction, stroke, heart failure, and venous thromboembolism in patients with cancer.

Methods

This was a register-based nationwide cohort study. Adjusted hazard ratios (aHRs) and 95% confidence intervals (95% CIs) for overall mortality and secondary outcomes were estimated using Cox proportional hazards models. Analyses were conducted separately for four subgroups: patients aged <65 years with solid tumors, patients aged ≥65 y

SUBMITTER: Amdisen L 

PROVIDER: S-EPMC11694166 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature