Association between latent toxoplasmosis and bipolar disorder: a case-control seroprevalence study.

ABSTRACT:

Background

Toxoplasma gondii (T. gondii) is the most successful obligate protozoan that can infect warm-blooded vertebrate hosts. Some researchers suggest that the presence of Toxoplasma cysts in the brain can lead to mental disorders. Bipolar disorder (BD) is one of the serious neuropsychiatric disorders. Several studies have shown a high seroprevalence of T. gondii in bipolar patients. Therefore, this study aims to determine the prevalence of this infection in patients with BD.

Methods

In this case-control study, anti-Toxoplasma immunoglobulin (Ig) G and IgM antibodies were measured in serum samples from 115 patients with BD and 115 subjects without this disorder from the general population using commercially available enzyme-linked immunosorbent assay. Demographic charact

SUBMITTER: Pagheh AS 

PROVIDER: S-EPMC11694387 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature