Chylothorax as an unusual manifestation of transthyretin cardiac amyloidosis: a case report.

ABSTRACT:

Background

Amyloidosis is a multi-organ disease of emerging significance in the field of cardiology. Chylothorax, a specific form of pleural effusion characterized by lymphatic fluid accumulation in the pleural cavity, is an extremely rare manifestation of amyloidosis. Notably, only five cases of chylothorax related to cardiac amyloidosis have been reported worldwide, all in amyloid light chain (AL) amyloidosis. No cases have been documented in amyloid transthyretin (ATTR) amyloidosis. Furthermore, elevated levels of serum carbohydrate antigen (CA) 125 have been associated with a poor prognosis in patients with AL cardiac amyloidosis.

Case summary

We report the case of an 85-year-old Austrian man with pronounced left ventricular hypertrophy, monoclonal gammopathy, and a hist

SUBMITTER: Poschl C 

PROVIDER: S-EPMC11694664 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature