MCHelper automatically curates transposable element libraries across eukaryotic species.

ABSTRACT: The number of species with high-quality genome sequences continues to increase, in part due to the scaling up of multiple large-scale biodiversity sequencing projects. While the need to annotate genic sequences in these genomes is widely acknowledged, the parallel need to annotate transposable element (TE) sequences that have been shown to alter genome architecture, rewire gene regulatory networks, and contribute to the evolution of host traits is becoming ever more evident. However, accurate genome-wide annotation of TE sequences is still technically challenging. Several de novo TE identification tools are now available, but manual curation of the libraries produced by these tools is needed to generate high-quality genome annotations. Manual curation is time-consuming, and thus impractica

SUBMITTER: Orozco-Arias S 

PROVIDER: S-EPMC11694758 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature