Birth prevalence and determinants of neural tube defects among newborns in Ethiopia: A systematic review and meta-analysis.

ABSTRACT:

Background

Neural tube defects (NTDs) are complex multifactorial disorders in the neurulation of the brain and spinal cord that develop in humans between 21 and 28 days of conception. Neonates with NTDs may experience morbidity and mortality, with severe social and economic consequences. Therefore, the aim of this systematic review and meta-analysis is to assess the pooled prevalence and determinants for neural tube defects among newborns in Ethiopia.

Methods

The protocol of this study was registered in the International Prospective Register of Systematic Reviews (PROSPERO Number: CRD42023407095). We systematically searched the databases PubMed, Science Direct, Cochrane Library, Google Scholar and Research Gate. Grey literature was searched on Google. Heterogeneity among stu

SUBMITTER: Gebremariam BM 

PROVIDER: S-EPMC11695007 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature