Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients With Crohn's Disease-Like Pouch Inflammation.

ABSTRACT:

Introduction

The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn's disease-like pouch inflammation (CDLPI) on therapy.

Methods

This was a single-center retrospective study of patients older than 18 years with CDLPI on therapy.

Results

Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared with endoscopic response.

Discussion

Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.

SUBMITTER: Kayal M 

PROVIDER: S-EPMC11695146 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature