Multi-epitope vaccines: a promising strategy against viral diseases in swine.

ABSTRACT: Viral infections in swine, such as African swine fever (ASF), porcine reproductive and respiratory syndrome (PRRS), and foot-and-mouth disease (FMD), have a significant impact on the swine industry. Despite the significant progress in the recent efforts to develop effective vaccines against viral diseases in swine, the search for new protective vaccination strategy remains a challenge. The antigenic epitope, acting as a fundamental unit, can initiate either a cellular or humoral immune response. Consequently, the combination of multi-epitopes expressing different stages of viral life cycle has become an optimal strategy for acquiring a potent, safe, and effective vaccine for preventing and treating viral diseases in swine. Recent progresses in immunoinformatic tools, coupled with an unders

SUBMITTER: Chen X 

PROVIDER: S-EPMC11695243 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature