Comparative transcriptomic and molecular biology analyses to explore potential immune responses to Vibrio parahaemolyticus challenge in Eriocheir sinensis.

ABSTRACT: Vibrio parahaemolyticus is a significant pathogen affecting shrimp and crab farming, particularly strains carrying genes associated with acute hepatopancreatic necrosis syndrome. However, the immune response of Eriocheir sinensis to V. parahaemolyticus infection remains unclear. To address this knowledge gap, an experiment was conducted to establish a V. parahaemolyticus infection model. This model aimed to compare pathological damage and enzyme activity changes in E. sinensis hepatopancreas tissue at various infection time points, and to examine transcriptome changes in individuals exhibiting different clinical symptoms of infection. The results showed that intramuscular injection of 1.78 × 10⁶ CFU/mL of V. parahaemolyticus for 24 hours

SUBMITTER: Chen D 

PROVIDER: S-EPMC11695290 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature