Development of a novel Haemabiome tool for the high-throughput analysis of haemopathogen species co-infections in African livestock.

ABSTRACT: One of the principal limitations on livestock productivity in sub-Saharan Africa is the constraining effect of infectious diseases, including tick-borne blood pathogens. Currently, diagnostic markers for these pathogens are species or genus specific, making it challenging to implement high-throughput screening methods. The aim of this study was to develop and validate a novel high-throughput diagnostic tool capable of detecting a range of important haemopathogens in livestock. To achieve this, we developed a high-throughput diagnostic tool that can detect all species of Anaplasma, Ehrlichia, Theileria and Babesia present in a sample. The approach involves targeting the 16S/18S rDNA region by PCR and subjecting amplicons to deep sequencing, which allows for the identifi

SUBMITTER: Yalcindag E 

PROVIDER: S-EPMC11695320 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature