DCUN1D5 is a prognostic biomarker and correlated immune infiltrates and glycolysis in lung adenocarcinoma.

ABSTRACT: DCUN1D5 is up-regulated and promotes tumor progression in many cancers such as laryngeal squamous cell carcinoma and breast cancer, but the expression of DCUN1D5 in lung adenocarcinoma and its molecular mechanism are not clear. The differences of DCUN1D5 expression between lung adenocarcinoma and normal tissues were compared by TCGA, GEO and UALCAN databases, and the relationship between DCUN1D5 expression and clinicopathological features of patients was analyzed. The diagnostic and prognostic value of DCUN1D5 in patients with LUAD was analyzed by TCGA, GEPIA and Kaplan-Meier Plotter database. nomogram was constructed to predict the survival probability of patients. The GO, KEGG and GSEA enrichment analysis of DCUN1D5 co-expression genes were completed by R software. R software and GEPIA2

SUBMITTER: Zhao S 

PROVIDER: S-EPMC11695623 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature