Quality of life after stereotactic radiosurgery for brain metastasis: an assessment from a prospective national registry.

ABSTRACT:

Purpose

Stereotactic radiosurgery (SRS) is frequently used in the management of brain metastasis patients. However, there is an urgent need to evaluate post-treatment outcomes and quality of life metrics for patients undergoing SRS for brain metastases.

Methods

The NeuroPoint Alliance (NPA) SRS Quality Registry conducted prospective enrollment of patients undergoing SRS from 2017 to 2024. Patients with brain metastases from lung cancer, breast cancer, and melanoma were included in the analysis. Outcomes of interest included quality of life metrics, as captured by the five-dimension Euro-QOL (EQ-5D) at 6-12 months and last record follow-up, overall survival, local progression, out-of-field progression, and overall intracranial progression.

Results

522 patients comprise

SUBMITTER: Pham DQ 

PROVIDER: S-EPMC11695642 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature