Association of triglyceride-glucose index with Helicobacter pylori infection in the 1999-2000 NHANES cross-sectional study.

ABSTRACT: Helicobacter pylori (H. pylori) infection is linked to metabolic syndrome and insulin resistance, with the triglyceride-glucose (TyG) index serving as a reliable marker for the latter. This study investigates the association between the TyG index and H. pylori infection. The study utilized cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999 and 2000. Participants underwent serologic testing for H. pylori, and the TyG index was calculated from fasting laboratory measurements. Multivariate logistic regression and restricted cubic spline methods were used to assess the association and explore the dose-response relationship. The analysis included 2984 participants. Elevated TyG index values were associated with an increased likelihood

SUBMITTER: Liu W 

PROVIDER: S-EPMC11695683 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature