Machine learning for early detection and severity classification in people with Parkinson's disease.

ABSTRACT: Early detection of Parkinson's disease (PD) and accurate assessment of disease progression are critical for optimizing treatment and rehabilitation. However, there is no consensus on how to effectively detect early-stage PD and classify motor symptom severity using gait analysis. This study evaluated the accuracy of machine learning models in classifying early and moderate-stages of PD based on spatiotemporal gait features at different walking speeds. A total of 178 participants were recruited, including 103 individuals with PD (61 early-stage, 42 moderate-stage) and 75 healthy controls. Participants performed a walking test on a 24-m walkway at three speeds: preferred walking speed (PWS), 20% faster (HWS), and 20% slower (LWS). Key features-walking speed at PWS, stride length at HWS, and

SUBMITTER: Hwang J 

PROVIDER: S-EPMC11695740 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature