International consensus definitions for infection-triggered encephalopathy syndromes.

ABSTRACT:

Aim

To develop standardized diagnostic criteria for 'infection-triggered encephalopathy syndrome (ITES)' and five specific clinical syndromes of ITES.

Method

The draft definitions were based on existing criteria, standardized, and discussed by a panel of international experts using nominal group technique over 18 months to achieve consensus. All criteria use the same format: (1) presence of infection/fever; (2) clinical features including encephalopathy; (3) neuroradiological features on magnetic resonance imaging; (4) exclusion of other causes.

Results

We first highlighted differences between ITES and infectious and autoimmune encephalitis, which is the most important differential diagnosis. Consensus was achieved to define five specific ITESs: acute encephalopathy w

SUBMITTER: Sakuma H 

PROVIDER: S-EPMC11695768 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature