KMetaShot: a fast and reliable taxonomy classifier for metagenome-assembled genomes.

ABSTRACT: The advent of high-throughput sequencing (HTS) technologies unlocked the complexity of the microbial world through the development of metagenomics, which now provides an unprecedented and comprehensive overview of its taxonomic and functional contribution in a huge variety of macro- and micro-ecosystems. In particular, shotgun metagenomics allows the reconstruction of microbial genomes, through the assembly of reads into MAGs (metagenome-assembled genomes). In fact, MAGs represent an information-rich proxy for inferring the taxonomic composition and the functional contribution of microbiomes, even if the relevant analytical approaches are not trivial and still improvable. In this regard, tools like CAMITAX and GTDBtk have implemented complex approaches, relying on marker gene identificatio

SUBMITTER: Defazio G 

PROVIDER: S-EPMC11695915 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature