TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury.

ABSTRACT: Practices for controlling intracranial pressure (ICP) in traumatic brain injury (TBI) patients admitted to the intensive care unit (ICU) vary considerably between centres. To help understand the rational basis for such variance in care, this study aims to identify the patient-level predictors of changes in ICP management. We extracted all heterogeneous data (2008 pre-ICU and ICU variables) collected from a prospective cohort (n = 844, 51 ICUs) of ICP-monitored TBI patients in the Collaborative European NeuroTrauma Effectiveness Research in TBI study. We developed the TILTomorrow modelling strategy, which leverages recurrent neural networks to map a token-embedded time series representation of all variables (including missing values) to an ordinal, dynamic prediction of the following day's

SUBMITTER: Bhattacharyay S 

PROVIDER: S-EPMC11696189 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature