Circulating CD3⁺CD8⁺ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer.

ABSTRACT: Circulating CD3⁺CD8⁺ cell levels were lower in breast cancer patients, elevated posttreatment, and subsequently declining upon recurrence. Elevated plasma chemokine (C-C motif) ligand 2 (CCL2) levels distinguished patients with breast cancer from healthy controls. In summary, circulating CD3⁺CD8⁺ CTL and plasma CCL2 levels emerged as promising dual-purpose biomarkers and therapeutic targets in breast cancer management.

SUBMITTER: Chen HK 

PROVIDER: S-EPMC11696249 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature