Cardiovascular Disease and Breast Cancer Stage at Diagnosis.

ABSTRACT:

Importance

Cardiovascular disease (CVD) and cancer are the leading causes of mortality in the US. Large-scale population-based and mechanistic studies support a direct effect of CVD on accelerated tumor growth and spread, specifically in breast cancer.

Objective

To assess whether individuals presenting with advanced breast cancers are more likely to have prevalent CVD compared with those with early-stage breast cancers at the time of diagnosis.

Design, setting, and participants

This population-based case-control study used data from the Surveillance, Epidemiology, and End Results-Medicare linked databases from 2009 to 2020. The analysis was completed from May 2023 to August 2024. Participants were female patients aged at least 66 years diagnosed with invasive breast c

SUBMITTER: Angelov I 

PROVIDER: S-EPMC11696447 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature