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Modulating synaptic plasticity with metal-organic framework for information-filterable artificial retina.


ABSTRACT: Neuroprosthetics equipped with artificial synapses hold promise to address some most intricate medical problems, such as human sensory disorders. Yet, it is necessitated and of paramount importance for neuroprosthetics to be able to differentiate significant and insignificant signals. Here, we present an information-filterable artificial retina system that integrates artificial synapses with a signal-integration device for signal perception and processing with attention. The synaptic weight modulation is rendered through metal-organic framework (MOF) layers, where distinct short-term and long-term properties are predominantly determined by MOF's pore diameter and functionality. Specifically, four types of isoreticular Zr-based MOFs that share Zr6O4(OH)4 sec

SUBMITTER: Kim S 

PROVIDER: S-EPMC11696553 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature